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Thus, notwithstanding the existing skepticism about the future development of these drugs, substantial optimism persists that new antiobesity drugs will be available in the foreseeable future

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Other symptoms of vitamin B12 deficiency Other symptoms of the condition are listed by Bupa as: Feeling very tired Breathlessness even after a little exercise Heart palpitations Headaches A reduced appetite A sore mouth and tongue The health organisation adds: If you have vitamin B12-deficiency anaemia, you may also look pale or jaundiced (have a yellowy tinge to your skin and the whites of your eyes)