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At the same time, neurotransmitters such as dopamine, serotonin, and norepinephrine finely tune taste responsiveness from individual taste buds to cortical reward pathways, ensuring adaptive eating behaviors ( The process of food intake, digestion and nutrient absorption is tightly coordinated through bidirectional signaling between the gastrointestinal tract and the central nervous system (CNS), collectively referred to as the gut-brain axis (GBA)

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In a separate 12-month prospective study of 65 patients with type 2 diabetes mellitus (T2DM) initiating GLP-1 RA therapy (dulaglutide or semaglutide), significant reductions in body weight and BMI were also observed

Post-marketing surveillance will be crucial after approval