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Evidence in observational human studies is requested in future to link animal study to human physiology

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doi: 10.1016/j.athoracsur.2008.09.026 [DOI] [PubMed] [Google Scholar] 49.Wang G, Bainbridge D, Martin J, et al

While the in vitro concentrations used in the included studies (ranging from 0.5 to 400 g/mL) are difficult to translate into real-world inhalation or dermal exposure levels, available human exposure proxies (e.g., PET-specific EDI from indoor dust 4150 g/kg-bw/day in infants [56]) suggest that quantitative alignment across routes and metrics remains uncertain