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These medications help people lose weight by suppressing appetite and slowing digestion, leading to lower food intake and, subsequently, significant weight reduction

However, while 16 days of L-citrulline supplementation at a daily dose of 3.4 g significantly increased plasma citrulline, arginine, and nitrite levels, and increased muscle oxygenation during moderate-intensity (70% VO 2 peak) exercise, there were no superior effects on time-to-exhaustion during high-intensity (90% VO 2 peak) exercise

People diet, lift weights, and do more cardio, but recently, people have turned to another option

hemsleyanum (Jiang et al., 2025)