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Research indicates that propionate undergoes conversion to glucose through intestinal gluconeogenesis prior to reaching the liver, conferring metabolic advantages in maintaining energy equilibrium ( Bacteroides fragilis , a bacterium that suppresses bile salt hydrolase activity, leading to a rise in secondary bile acids like GUDCA
Of note, a significant decrease in total, LDL-cholesterol and in triglycerides has been revealed following CAB therapy in male hyperprolactinemic patients with concomitant hypogonadism, with no further improvement in lipid profile after 12 months of testosterone replacement therapy (52)
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Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS
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