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FOXO4-DRI has been investigated extensively in preclinical academic literature for p53 transactivation domain binding, senescence-associated apoptosis pathway research, p16 and IL-6 marker dynamics in senescent cell research models, and SASP (senescence-associated secretory phenotype) signaling

Rev Col Bras Cir 39:515520 Belmehdi O, El Menyiy N, Bouyahya A, El Baaboua A, El Omari N, Gallo M, Montesano D, Naviglio D, Zengin G, Skali Senhaji N, Goh BH, Abrini J (2022) Recent advances in the chemical composition and biological activities of propolis

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