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Int Arch Allergy Appl Immunol, 75: 255-263

The initial outcome of the mitochondrial respiratory chain is the generation of O 2 , which is formed at numerous mitochondrial locations, encompassing NADH:ubiquinone oxidoreductase (complex I), succinate dehydrogenase (complex II), ubiquinol:cytochrome c oxidoreductase (complex III), and mitochondrial glycerol 3-phosphate dehydrogenase [15]

While early treatment to correct for vitamin B12 deficiency is absolutely imperative to the babys recovery, it is unfortunately often a situation of too little, too late. Tragically, vitamin B12 deficiency in babies results in irreversible brain injury in approximately 50% of cases, even after B12 deficiency is corrected with supplementation

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