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Age 50+ (higher NAION risk) Pre-existing GI issues (gastroparesis risk) Eye conditions or family history of vision problems Using for weight loss only (off-label, potentially higher risks) Ask: Am I at higher risk for complications based on my health profile? The Bottom Line: Is the Risk Worth It

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Additionally, Met has been shown to induce the mTOR complex 1 activation (Kitada et al., 2020), which regulates the synthesis of all proteins in the body, including enzymes, thereby reinforcing its importance for both milk yield and milk protein synthesis (Praynat et al., 2009)

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