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Proteins that regulate ferroptosis are GPX4 (glutathione peroxidase 4), cystine/glutamate antiporter System Xc, iron homeostasis, and some enzymes associated with lipids synthesis such as (Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) and Lysophosphatidylcholine Acyltransferase 3 (LPCAT3) [249, 250]

Since the drugs have come on the market, declines in obesity rates have been higher among those between ages 40 and 64, correlating with a higher reliance on GLP-1 medications for that age group

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