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The reason I say this is because with Triumph-1 Eli Lilly only had the raw trial data for a couple weeks, so they scrambled to pull out the stuff thats relevant to a conference such as this meaning any deeper exploration on the liver and kidney were left out

Renal impairment GLP-1 RAs are generally safe in patients with CKD and have demonstrated nephroprotective effects in the FLOW trial, where semaglutide significantly reduced the composite renal endpoint (hospitalization for acute kidney injury, sustained 50% decline in estimated glomerular filtration rate (eGFR), end-stage kidney disease, or renal death) in patients with type 2 diabetes and CKD [15]

Prescription restrictions In India, GLP-1 drugs can only be prescribed by endocrinologists, internal medicine specialists, and cardiologists

Weight loss and improved insulin sensitivity can lead to favorable hormonal changes, including increased testosterone levels in men with obesity-related hypogonadism and improved ovulatory function in women with PCOS