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National Center for Biotechnology Information (US) Bertoglio D, Amhaoul H, Van Eetveldt A, Houbrechts R, Van De Vijver S, Ali I, Dedeurwaerdere S (2017) Kainic acid-induced post-status epilepticus models of temporal lobe epilepsy with diverging seizure phenotype and neuropathology

It causes small, red, and sometimes scaley lesions called papules

It is mainly produced by the liver (accounting for 75 % of circulating IGF-1) secondary to growth hormone (GH) and insulin endocrine stimulation in the liver