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Furthermore, leptin receptor-deficient mice, a mouse model of obesity and diabetes, and people with endogenous glucagon deficiency (pancreatectomised individuals) treated with glucagon antisense oligonucleotide have increased hepatic fat [52, 53]
The anti-inflammatory, antioxidant, and immunomodulatory properties of MSCs have shown promise in ameliorating PCOS, primarily through the secretion of bioactive factors or by direct cell-to-cell interactions
