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2013;8(10):e77284

It is commonly employed in longevity and age-related signaling models, where researchers examine endpoints such as gene expression patterns, cellular stress responses, and telomere-related pathways in preclinical or in vitro systems

Your body might see them as foreign and start to developed antibodies

In a double-blind, placebo-controlled trial in 11 smokers and 13 nonsmokers given -tocopherol and -tocopherol that was labeled with deuterium, supplementation with vitamin C reduced the rate of vitamin E loss in plasma, likely by regenerating tocopheryl radicals back to nonoxidized forms (22)