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Species interaction at the cellular level, dispersion or intercellular lipids extraction, increased fluidity of stratum corneum lipid bilayers, higher drug thermodynamic activity, and greater SC hydration are all mechanisms that support drug administration using chemical enhancers [283]

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[ 6 ] Additionally, throughout the 1980s, DSIP was also researched for its potential influence on endocrine function, stress response, pain perception, and the effects of drugs such as morphine and amphetamines

Treatment decisions should be made only after consultation with a licensed healthcare provider