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Mnnist, S., Kontto, J., Kataja-Tuomola, M., Albanes, D., & Virtamo, J

Impact of treatment with GLP-1RAs on suicide attempts in adults persons with type 2 diabetes: A retrospective comparative effectiveness study based on a global TriNetX health research database

EDP-305 is a novel oral FXR agonist under development for the treatment of MASH

The major difference is molecular structure: orforglipron is a non-peptide small molecule that survives digestion, while semaglutide is peptide-based and requires injection