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S.StoberF.et al (2016)

Findings for single supplements (e.g., curcumin, other polyphenols, CoQ10 and multi-strain probiotics) are mixed and inconsistent, and existing RCTs of ALA have not demonstrated clinical benefit

In particular, they're both great sources of essential minerals, particularly copper and iron

If youre concerned that your dog may be deficient in B12, or if your dog is suffering from chronic gastrointestinal symptoms, its best to see your veterinarian for a physical exam