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Nature PubMed Preclinical literature and narrative reviews describe pleiotropic actions including angiogenesis modulation (promotion in healing contexts and proposed inhibition in rodent corneal neovascularization models) and purported cytoprotective effects across diverse injury paradigms, but these remain unconfirmed in controlled human experiments

Japans first-in-class obesity approval in early 2024 delivered strong initial uptake

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These findings suggest that tirzepatide may have favorable effects on cardio metabolic risk variables such as blood pressure, waist circumference, and lipid profile [77]