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Several case reports have documented its success in helping patients with cardiovascular collapse due to overdoses recover without any adverse cardiovascular or neurological effects.[14,15,16] While early literature reviews showed mixed support on ECMO use in overdose, a large systematic review of therapies used in calcium channel blocker overdoses found that ECMO was only one of two therapies (with the other being HDI) that was supported by the strongest evidence

There is no known interaction between the two that requires specific timing separation

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In another study, it increased blood vessel formation in damaged muscles and tendons, resulting in improved healing [4]