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HYGIENE A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS A61P25/00Drugs for disorders of the nervous system A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g

The cytoplasmic tyrosine phosphorylation (P) sites of the c-Met are indicated: Tyr1003 is in the juxtamembrane binding site, Tyr1234 and Tyr1235 are in the active site of the kinase and Tyr1349 and Tyr1356 are in the bidentate docking site (Fig