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Elevated cAMP leads to activation of protein kinase A, which regulates key enzymes involved in triglyceride breakdown

The aortic ring assay (ex vivo sprouting from rat aortic rings embedded in Matrigel), Matrigel plug assay (in vivo CD31-stained vessel density), and HUVEC tube formation assay (Angiogenesis Analyser quantification) all demonstrate robust, reproducible BPC-157-driven angiogenesis