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Coverage varies widely depending on the insurance provider and the reason for prescription

Continuing to cover weight loss drugs for even a small portion of them could easily add billions per year to an already strained budget

Since these formulations are regulated differently from name brands, there is often inconsistency in how they are assembled, labeled, and dosed, making it challenging for doctors to understand exactly what their patients are taking and how it might affect them

For example, adalimumab as a TNF inhibitor blocks the bind of TNF and its receptors to reduce cytokines (like MMP-1 and MMP-3)-driven inflammatory processes, which suppresses the destruction of cartilage and bone (72)