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10.1038/nchembio.209 73

GLP-1 medications, without exercise, often cause muscle loss, slowing metabolism over time

Semaglutide is a GLP-1 receptor agonist that lowers blood sugar and reduces appetite by slowing gastric emptying and signaling fullness to your brain

A previous study indicated that treatment with the GLP-1 agonist liraglutide (subcutaneously at a dose gradually titrated from 0.6 to 3 mg) in bipolar and mood disorder depression patients could result in an improvement in cognitive function and an alleviation of depressive pathological symptoms ( Considering this evidence, increasing neurogenesis in the brain through the GLP-1 pathway may provide a novel approach for improving depressive-like behavior in patients with depression