At iThrive, we always recommend deeper testing first through Book a Root Cause Analysis when any of you stated unexplained B12 deficiency, ongoing fatigue, and digestive issues despite taking supplements
Most recently, a randomized controlled trial published May 3, 2025, in The Lancet found that a GLP-1 boosted walking ability and quality of life in people with PAD and diabetes
Some symptoms warrant immediate medical attention: Severe or worsening abdominal pain Blood in your vomit or stool Fever Stiff neck The worst headache youve ever had Persistent vomiting or abdominal pain The inability to keep fluids down Excessive nausea, vomiting, or abdominal pain while pregnant Unintentional or unexplained weight loss Diagnosis: How clinicians pinpoint the cause To help determine the cause of your nighttime nausea, a clinician will likely do the following: Ask you about your medical history (and that of your family) to learn about your underlying conditions and risk factors Ask you about your medications and supplementsas well as any side effects Ask you questions about your symptoms, including their frequency, duration, and severity Ask you about your lifestyle habits, including diet, meal times, alcohol consumption, and more Ask you about your mental health, including your stress and anxiety levels Examine you if necessary Order any necessary lab work or imaging tests Treatment options The treatment options for nocturnal nausea will vary based on the underlying cause
Whitfield et al., 2016)
