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This study is the first to describe the role of ferroptosis in fat graft survival and demonstrate the potential of this pathway as a therapeutic target for improving lipotransfer success

But, the role of glutathione in both health and disease has been extensively studied, and its understood that a chronically low glutathione level is associated with higher mortality

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As with the skin work, the framing in published reviews remains observational with respect to mechanism, and most authors note that the in vivo translation outside of topical and injected animal-model contexts is not fully characterized