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In an interview with the US channel CBS, she says she could cry thinking back to the days and nights she journaled about how being overweight was her fault and Why cant I conquer this thing? She has shared the experience in a new book, written in collaboration with Dr Ania Jastreboff from the Yale School of Medicine, called Enough: Your Health, Your Weight, and What Its Like To Be Free

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[4] [5] In the brain, GLP-1 receptor activation in appetite-regulating centers reduces hunger and increases satiety, leading to decreased caloric intake and weight loss

Think of it this way: without training, your body treats muscle and fat relatively equally as energy sources during a deficit