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7 Researchers from the 2020 study also noted that the increase in vitamin B12 was likely unrelated to typical dietary intake or standard supplementation because food and supplements generally do not substantially affect plasma B12 concentrations

Metformin: This diabetes medication might impair vitamin B12 absorption in some people

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Quick Reference: Injectable Protocol Community-reported starting doses cluster around 200 mg 2-3 times per week, with functional medicine protocols describing doses up to 600 mg per session