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The tesofensine article covers a compound that approaches weight loss through neurotransmitter modulation, providing appetite suppression through a completely different mechanism than GLP-1 agonists

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Short-term use (1-2 weeks) may be sufficient for some, while others may require longer periods (4-6 weeks or more) to achieve their goals

Manufacturer in the USA, Mexico, and Canada 1 USA: Novo Nordisk Inc