Int J Pediatr Otorhinolaryngol 120:1519 Noack V, Pak K, Jalota R, Kurabi A, Ryan AF (2017) An antioxidant screen identifies candidates for protection of cochlear hair cells from gentamicin toxicity
Histone deacetylases including SIRT1, interact with STAT3 and negatively regulate its transcriptional activity by deacetylating critical lysine residues (Nie et al., 2009)
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On the one hand, microbial metabolites such as short-chain fatty acids and secondary bile acids stimulate GLP-1 secretion from intestinal L-cells and modulate its circadian rhythm, linking microbial activity to satiety regulation, glucose control, and fat metabolism (Figure 2, left)