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The degradation rate and half-life (t1/2) of the drugs were determined by measuring the decrease in area under the curve (AUC) at their retention times [2]
Four weeks post-transplantation, widespread hALB-positive cells were observed, and FACS analysis showed that approximately 15% of the total hepatocyte mass was derived from the transplanted human HBs, with increasing hALB secretion in the mouse serum over time [1]
These behavioral benefits are underpinned by its marked ability to induce spinogenesis and promote functional synaptogenesis in hippocampal neurons, highlighting its potential as a robust procognitive and antidementia agent [2]
HLC cultures were incubated with conventional probe substrates for CYP3A4 (6 M midazolam), CYP2C9 (10 M diclofenac), and CYP2D6 (10 M dextromethorphan) for 2 hours
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