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Shaking can cause the delicate peptide chains to break apart or denature, which may render the compound ineffective

Room temperature dramatically accelerates degradation

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[PubMed] [Google Scholar] 281.Cesarec V., Becejac T., Misic M., Djakovic Z., Olujic D., Drmic D., Brcic L., Rokotov D.S., Seiwerth S., Sikiric P