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Data presented herein support the notion that prolonged exposure to GLP-1R stimulation can also induce glucose competence by a secondary mechanism involving up-regulation of glycolytic enzymes, and consequently glycolytic flux, arguably the most important stimulus-secretion coupling factor generating pathway in -cells

In the 1970s, some research suggested that high doses of Vitamin C could "destroy" Vitamin B12 in a test tube environment

Different mechanisms of GIP and GLP-1 action explain their different therapeutic efficacy in type 2 diabetes

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