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Protocols should include explicit thresholds for ER referral (persistent vomiting, severe abdominal pain, visual changes suggesting diabetic retinopathy progression) and dose adjustment criteria

The risk of low blood sugar (hypoglycemia) remains low unless combined with other diabetes medications like insulin

The resulting peptides are analyzed using high-resolution LC-MS/MS

News-Medical+3EurekAlert!+3ASMBS+3 To put numbers on it: Surgical patients lost ~58 lbs in two years ( 24% of total body weight, or TBW) GLP-1 patients lost only ~12 lbs ( 4.7% TBW) over the same period EurekAlert!+2News-Medical+2 Even among GLP-1 users who continued therapy for a full year, weight loss averaged only ~7% TBWstill far less than surgical outcomes EurekAlert!+2ASMBS+2 Another rigorous analysis published in JAMA Surgery compared weight loss surgery and GLP-1 receptor agonists over two years