AOD-9604 is a much more targeted tool
Skin Aging and Collagen Loss Skin aging involves several structural changes: reduced collagen synthesis increased collagen degradation decreased elastin integrity slower cellular turnover These processes contribute to wrinkles, skin laxity, and reduced resilience
Eur J Pharmacol 319:369373 Sebhat IK, Martin WJ, Ye Z, Barakat K, Mosley RT, Johnston DB, Bakshi R, Palucki B, Weinberg DH, Macneil T, Kalyani RN, Tang R, Stearns RA, Miller RR, Tamvakopoulos C, Strack AM, Mcgowan E, Cashen DE, Drisko JE, Hom GJ, Howard AD, Macintyre DE, Van Der Ploeg LH, Patchett AA, Nargund RP (2002) Design and pharmacology of N-[(3R)-1,2,3,4-tetrahydroisoquinolinium- 3-ylcarbonyl]-(1R)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1H-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (1), a potent, selective, melanocortin subtype-4 receptor agonist
[13] [14] While a brief period at room temperature (such as during administration) is acceptable, prolonged exposure above 86F (30C) can render the medication less effective or potentially inactive