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Since its India launch in March 2025, Mounjaro has accumulated 233 crore in total sales, capturing significant market share in the obesity and diabetes drug segment

In recent years, advances in cryo-electron microscopy (cryo-EM) have enabled structural determination of a large number of class B1 GPCRs bound to their endogenous agonists, and coupled to G s , including that of the GLP-1R, which confirm engagement of these peptides with both the ECD and the TMD 10,11,12,13,14,15,16,17,18,19,20,21

However, vitamin B 12 deficiency does not generally develop until after at least two-to-three years of continuous therapy (137-139)