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Current indications for semaglutide are limited to patients with both CKD and T2D, although this may evolve with future research

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For example, the study found GLP-1 users had a 7% greater risk of developing gastroparesis compared with people who were using other types of medications to lower their blood sugar

While often dismissed as minor side effects, these symptoms can indicate changes in fermentation patterns and gut transit that affect the microbiome more broadly