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Mitochondrial replacement therapy (MRT) The two basic methods for performing MRT are maternal spindle transfer (MST) and pronuclear transfer (PNT), which improve reproductive success by transferring the nuclear genome from the affected oocyte (MST) or fertilised egg (PNT) to the donors healthy cytoplasm [46]

Where they overlap Despite the mechanistic divergence, there is real overlap: Both promote wound healing in published animal models , though the dominant mechanism differs (ECM remodeling for GHK-Cu

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