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The most significant risk is rapid weight loss triggering gallstone formation and pancreatitis, particularly in patients with predisposing factors

In an azoxymethane/DSS-induced colorectal cancer mouse model, kefir supplementation modulated gut microbiota composition, reducing the relative abundance of Clostridium and Aspergillus , while decreasing inflammatory markers and cancer cell proliferation (Zeng et al., 2021)