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If you're eating far fewer calories than your body needs, fatigue becomes a natural response, similar to what happens during restrictive dieting

Furthermore, the high degree of heterogeneity in treatment effect highlights the need for identifying predictors of response to pharmacotherapy for weight-loss maintenance. For more information: Aaron Kelly, PhD , can be reached at [email protected].

Esters of sterols have a higher activity and better fat solubility, which allows for lower effective dosages (23 grams/day as opposed to 510 grams/day for unesterified sterols)