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The labeled cDNAs were used to detect marker genes of signal transduction pathways on microarray membranes using Human Signal Transduction PathwayFinder RT 2 Profiler PCR Array (SuperArray System, Bioscience, Frederick, MD, USA)

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However, covalent modification of the 20S proteasome by MG reduces its degradation activity, leading to persistent activation of the unfolded protein response (UPR), which ultimately triggers apoptosis and inflammatory responses (129, 130)

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