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Ang-II stimulating AHMs may mitigate dementia risk by preserving AT2 receptor function, that supports memory and neurogenesis, and by blocking AT1 receptors that mediate harmful effects such as oxidative stress, amyloid accumulation, and acetylcholine inhibition 33,34,35,36

A typical preparation combines hydroquinone (48%), tretinoin (0.0250.05%), and fluocinolone acetonide (0.01%) in a single topical cream

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