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Acquired cystic fibrosis transmembrane conductance regulator dysfunction in the lower airways in COPD

Saudi J Biol Sci 29(6):103278

Many of these approaches have yielded notable clinical success

Several natural flavonoids are known to block cyclins and cyclin-dependent kinases (CDKs), consequently inducing G0/G1 or G/M arrest in cancer cells (Figure 1) 43