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10.1016/j.tiv.2008.02.013 7 ChoiH.-R.KangY.-A.RyooS.-J.ShinJ.-W.NaJ.-I.HuhC.-H.et al (2012)

In the current review, we discussed the dysregulation of IGF-1/GLP-1 signaling in neurodegenerative manifestations of ALS like a genetic anomaly, oligodendrocyte degradation, demyelination, glial overactivation, immune deregulation, and neuroexcitation