mounjaro tirzepatide patent expiry As Novo's expires, GLP-1 generics go global The Heavy Price of GLP-1

Gut microbiota imbalance often involves fewer beneficial bacteria that produce short-chain fatty acids and a rise in harmful species, such as Proteobacteria and Bacteroidetes

(2024) Diabetes Care, 47(11):18731888 Frontiers in Endocrinology (2024) GLP-1 receptor agonists: gastrointestinal physiology and metabolic regulation Yoon HS et al

Literature reports suggest that vascular endothelial growth factor and hypoxia-inducible factor-1 signals can be transmitted through TNTs between malignant ovarian cancer cells and human vascular endothelial cells to write vascular endothelial growth factors [95]

Weight loss , whilst not the primary licensed indication in the UK for Ozempic, is a commonly observed effect