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At first, Wegovy was FDA-approved for chronic weight management when paired with exercise, dietary modifications, and increased physical activity in patients with obesity (body mass index 30 kg/m or more) and overweight (BMI 27 kg/m or more) with at least one weight-related health condition such as heart diseases, high blood pressure (hypertension), high cholesterol levels, type 2 diabetes, and sleep apnea

The first and most effective is continued treatment at a maintenance dose

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For optimal weight management, medications like Ozempic are most effective when combined with lifestyle changes