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Generation of strains using CRISPR-Cas9 Endogenous tagging of APTF-2 with GFP using CRISPR-Cas9 A C-terminal GFP knock-in strain for endogenous aptf-2 was generated using CRISPR/Cas9-triggered homologous recombination 67

REACCIONES SECUNDARIAS Y ADVERSAS: Orlistat: Las reacciones secundarias que se presentan con el uso de orlistat son en su mayora limitadas al tracto gastrointestinal, causadas por la inhibicin en la absorcin de grasas e incluyen heces lquidas o reblandecidas, heces grasosas, aumento en la defecacin, incontinencia fecal, dolor abdominal, goteo grasoso por ano, nusea y vmito

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