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Histology and immunohistochemistry (IHC) staining Adipose tissues and livers were fixed in 10% formalin (Sigma-Aldrich, #HT501320) for 24 36 h at 4 C

Targeting insulin receptors and downstream factors such as PI3K, mTOR, HIF-1 may help us inhibit tumor progression and restore drug sensitivity in pancreatic cancer

Moreover, she highlights that some people using these drugs to manage glucose levels dont want to lose any weight, for example, if they take medications for type 1 diabetes or addiction disorders

Success stories and a checklist for future directions are presented to encourage further research in this area