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In some models, GHK combined with external interventions such as laser exposure or dressing formulations appeared to accelerate wound contraction, vascular development, and epithelialization

After four treatment cycles (each lasting 12 months), the plaque was 99.3% smaller than its initial volume, and the calcification within the plaque was further reduced in size

Finally, we critically re-evaluate clinical evidence and propose an integrated future direction, arguing that the full potential of SFN will be realized only through a precision medicine approach that accounts for the complex interplay from farm to fork, and from fork to physiology

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