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StatPearls notes that high-dose oral B has been shown effective for maintenance, but recommendations are to always use the parenteral route in severe neurological manifestations
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On the other hand, in the Lurcher cerebellum, a decrease in glutamate neurotransmitter concentration has been observed [105], which is mainly released by the granular cells in the cerebellum [111]
Severe cases can develop into chronic ulcers, strictures, and even perforations, significantly impacting patients quality of life and treatment compliance [4,5,6]
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