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( i ) Quantification of H2AX foci in cells expressing empty vector or CCNE1 transduced with shRNAs targeting TMLHE alone (shTMLHE) or supplemented with propionylcarnitine or butyrylcarnitine (n = 3 technical replicates representative from 2 independent experiments in each cell line)

Significant increases were observed in plasma levels of 8-iso-prostaglandin F2, zeaxanthin, and skin carotenoids in the test group, compared to the control group, which showed no changes